Adaptation of a Repeated
Acquisitions Performance (RAP) procedure to a new olfactory apparatus is
described. The present study also examined the effects of a selective GABAa a5 inverse agonist, RY-24, on learning in rats. In each session the animals were exposed to
performance trials where the olfactory discrimination remained the same across
sessions and acquisition trials where they were required to learn a new
discrimination during the session.
Administration of RY-24 impaired functioning at higher doses but did not
produce selective effects on learning at any dose.