Graduate Course Descriptions

CHM 501. Introduction to Chemical Research (2) Scientific proposal and manuscript preparation. Communication techniques. Experimental design and data analysis. Computer applications. Library use. Laboratory safety. Two hours each week.

CHM 515. (415) Physical Organic Chemistry (3) Prerequisite: Two semesters of organic chemistry. Theoretical and physical organic chemistry, including chemical bonding, stereochemistry, and conformational analysis with applications to selected reaction mechanisms.

CHM 516. Advanced Organic Chemistry (3) Prerequisite: Two semesters of organic chemistry. Study of contemporary synthetic organic chemistry. Topics may include chiral synthetic methods, natural products synthesis, bioorganic chemistry, relationships between structure and reactivity and the role of reactive intermediates, with emphasis placed on examples from the recent literature.

CHM 517. (417) Medicinal Chemistry (3) Prerequisite: Two semesters of organic chemistry. Systematic study of the chemistry and biological activity of hormones, vitamins, drugs affecting the nervous system, and other miscellaneous agents.

CHM 520 (420). Quantum Mechanics (3) Prerequisite: Physical chemistry. The study of quantum mechanics, including the quantum mechanical description of chemical bonding, molecular orbital theory, and the quantum mechanical basis of microwave, IR and UV spectroscopies.

CHM 521. Advanced Physical Chemistry (3) Prerequisite: CHM 520 (420) or equivalent. The study of quantum statistical mechanical basis of thermodynamics, including the behavior of solids and liquids. Kinetics of chemical reactions, particularly the microscopic picture of chemical reactions based on quantum statistical mechanics.

CHM 522. Rates and Mechanisms (3) Prerequisite: Physical chemistry. Chemical kinetics and reaction mechanisms. Transition state and collision theories. Catalysis.

CHM 525 (424) Computational Chemistry (3) Prerequisite: Physical chemistry. Theory and practice of computational chemistry, including molecular mechanics, semi-empirical and ab initio molecular orbital theory, density functional theory, and molecular dynamics. Two lecture and two computer lab hours each week.
CHM 535. (435) Analytical Chemistry (2) Prerequisites: Physical chemistry and quantitative analysis or equivalent. Theory of modern analytical instrumentation and techniques. Normally taken concurrently with Analytical Chemistry Laboratory (CHML 535).

CHML 535. (435) Analytical Chemistry Laboratory (2) Prerequisite or corequisite: CHM 535. Applications of modern analytical instrumentation and techniques. Four laboratory hours each week.

CHM 536. Advanced Analytical Chemistry (3) Prerequisite: Organic chemistry. Application of modern analytical methods to chemical problems. Emphasis upon chemical information, structural and quantitative, obtainable from these techniques. Topics may include modern spectroscopic, chromatographic, electrochemical or bioanalytical techniques.

CHM 545. (445) Inorganic Chemistry (3) Prerequisite: Physical chemistry and quantitative analysis, or equivalent. Study of periodic relationships: crystal lattice theory; transition metals and ions; crystal field theory; organometallic structures and reactions; and reaction mechanisms.

CHM 546. Advanced Inorganic Chemistry (3) Prerequisite: CHM 545 or equivalent. Study of contemporary inorganic chemistry. Topics may include organometallic or bioinorganic chemistry and/or group theoretical treatment of current topics in inorganic chemistry.

CHM 565-566. (465-466) Biochemistry (3-3) Prerequisites: Cell biology, physical chemistry and two semesters of organic chemistry. The structures of macromolecules, amino acids, and vitamins, and the chemical principles governing their activities. Solution properties of macromolecules, enzyme kinetics and mechanisms, and metabolism emphasizing organic/physical chemistry. Biosynthesis of macromolecules. Chemistry and enzymology of nucleic acids.

CHM 567. (467) Biochemical Techniques and Instrumentation (2) Prerequisite or corequisite: CHM 566 or equivalent. Theory and practice of advanced biochemical techniques. Topics may include buffer and reagent preparation, protein assay, protein purification, electrophoresis, enzyme kinetics, vesicle construction, DNA isolation, and molecular visualization and modeling. Four hours each week.

CHM 575. (475) Chemical Oceanography (3) Prerequisite: General chemistry. An oceanography course is recommended. Sources, distribution, forms of occurrence, and reactions of chemical species in seawater. Estuarine reactions, air�seawater and sediment�seawater reactions, and human impact on the oceans.

CHM 576. (PHY 576) Chemical and Physical Analysis of Seawater (3) Prerequisite: Permission of instructor. Study of modern chemical and physical measurements of seawater including salinity, alkalinity, pH nutrients, and dissolved oxygen. Several class periods may also be devoted to working aboard an oceanographic research vessel while at sea.

CHM 585. Industrial and Polymer Chemistry (3) Prerequisites: Physical chemistry and two semesters of organic chemistry. Properties, synthesis, and reactions of major industrial chemicals; synthetic plastics, polyesters, polyamides, and rubbers; soaps and detergents; petrochemicals; paints and pigments; dyes; explosives; pulp and paper; pharmaceutical and nuclear industries; mechanism of polymerization; copolymerization; physical and chemical properties of polymers; polymer characterization; advances in polymer technology.

CHM 590. Special Topics (1�3) Study of a topic or technique in chemistry not covered in regular courses. May be repeated for credit.

CHM 591. Directed Individual Study (1�6) Directed Independent Study.

CHM 595. Graduate Seminar (1) Discussion by students, faculty, and guest lecturers of research ideas and/or research results. May be repeated two times for credit

CHM 599. Thesis (3�6) Laboratory research for thesis and thesis preparation.

NOTE: Students should complete all, or at least most, of their course work during their first year.
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