Organic and Inorganic Synthesis

Thomas Coombs
  • Development of new methods for organocatalytic alpha-amination of aldehydes.
  • Diversity-oriented synthesis of alkaloid-inspired compound collections for medicinal applications.
  • Exploration of the properties and reactivity of strained organosilanes.
Bart Jones
Dr Bart Jones
  • Electrochemistry of organometallic species such as (MeCp2ZrH2)2
  • Determination of acidity of Cp protons in CpReL3L2L3 species
  • Trace analysis method development using electrochemistry, spectroscopy, and chromatography.

Dr. John Tyrell
  • Organic synthesis and methodology: regioselective aromatic substitutions.
  • Polymer precursors and catalysis: development of synthetic methods for monomers; synthesis of heterocyclic ligands for polymer catalysis.
  • Industrially relevant research: determination of the fate of a heterocyclic compound used in water purification; extension of the scope of existing uses of a supported transition metal compound; development of analytical techniques for process streams.
Robert Hancock Picture Dr.Robert Hancock
  • Computer-aided design of ligands for use in medical imaging (MRI, PET), fluorescence-based sensors, and metal ion separations such as removal of radioactive isotopes from nuclear waste.
  • Study of complexing of metal ions by NMR, polarography, potentiometry, UV-visible and IR spectroscopy, X-ray crystallography, and fluorescence measurements.
  • Study of complexing of metal ions by NMR, polarography, potentiometry, UV-visible and IR spectroscopy, X-ray crystallography, and fluorescence measurements.
Sridhar Varadarajan Picture
Dr. Sridhar Varadarajan
  • Organic synthesis of DNA-alkylating molecules.
  • Design, organic synthesis, and investigation of molecules that target specific receptors on cells.
  • Targeting specific cell-types with DNA-damaging agents that induce cell-death, but not mutations, for potential therapeutic applications in diseases such as cancer and diabetes.

Dr. Pam Seaton
  • Isolation, synthesis, and structure elucidation of bioactive marine lipids.
  • Synthesis and NMR characterization of bioactive heterocycles.
Dr. Jeremy Morgan Image
Dr Jeremy Morgan
  • New transition metal-catalyzed and organocatalytic methods for the synthesis of chiral, non-racemic organic molecules.
  • Catalyst development and study of reaction mechanism.
  • Application in bioactive natural product total synthesis.

 


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